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miRSystem
is a database which integrates seven well known miRNA target gene prediction programs:
DIANA
,
miRanda
,
miRBridge
,
PicTar
,
PITA
,
rna22
, and
TargetScan
.
This database contains validated data from
TarBase
and
miRecords
on interaction between miRNA and its target genes.
Several new features which distinguish
miRSystem
from others:
1) miRSystem allows querying multiple miRNAs in one step for the associations between the miRNAs and their target genes.
2) Two algorithms are incorporated to characterize the enriched biological functions/pathways among the genes targeting by queried miRNAs.
*Currently we only support
Homo sapiens and Mus musculus
miRNAs.
How to cite miRSystem: (
View
)
Tzu-Pin Lu, Chien-Yueh Lee, Mong-Hsun Tsai, Yu-Chiao Chiu, Chuhsing Kate Hsiao, Liang-Chuan Lai, Eric Y. Chuang. (2012) miRSystem: An Integrated System for Characterizing Enriched Functions and Pathways of MicroRNA Targets. PLoS ONE 7(8): e42390. doi:10.1371/journal.pone.0042390
Bioinformatics and Biostatistics Core, NTU Center of Genomic Medicine